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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD4
All Species:
22.12
Human Site:
S45
Identified Species:
44.24
UniProt:
Q9Y227
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y227
NP_001122402.1
616
70255
S45
S
V
L
A
A
A
V
S
L
L
Y
F
S
V
V
Chimpanzee
Pan troglodytes
XP_519659
710
80224
S147
S
V
L
A
A
A
V
S
L
L
Y
F
S
V
V
Rhesus Macaque
Macaca mulatta
XP_001108472
728
82237
S165
S
V
L
A
A
A
V
S
L
L
Y
F
S
V
V
Dog
Lupus familis
XP_543243
608
69462
S45
S
I
L
A
A
A
V
S
L
L
Y
F
S
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT4
613
69727
S45
S
I
L
A
A
A
V
S
L
L
Y
F
S
V
V
Rat
Rattus norvegicus
P97687
511
57389
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507040
633
71884
S61
G
V
L
A
A
A
A
S
L
L
Y
Y
S
V
V
Chicken
Gallus gallus
P79784
495
54515
Frog
Xenopus laevis
NP_001088548
616
70594
L45
G
A
A
A
V
I
L
L
L
L
I
Y
S
L
L
Zebra Danio
Brachydanio rerio
NP_001002419
611
69763
G45
G
L
L
A
G
V
M
G
L
L
Y
L
L
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
V35
E
A
H
T
S
P
K
V
I
A
D
D
Q
E
R
Sea Urchin
Strong. purpuratus
XP_785341
537
60729
R19
A
F
W
H
I
S
F
R
L
T
H
L
R
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
82.2
93.5
N.A.
93
26.4
N.A.
86.5
24.5
77.1
70.6
N.A.
N.A.
N.A.
30.6
48.5
Protein Similarity:
100
85.4
82.8
96.4
N.A.
97.5
47.4
N.A.
92
42.6
88.4
84.2
N.A.
N.A.
N.A.
48.8
63.3
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
80
0
26.6
40
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
86.6
0
53.3
60
N.A.
N.A.
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
9
67
50
50
9
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
9
0
0
0
0
9
0
0
0
0
42
0
0
0
% F
% Gly:
25
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
9
9
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
17
0
0
9
9
0
0
9
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
59
0
0
0
9
9
75
67
0
17
9
17
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
9
9
9
% R
% Ser:
42
0
0
0
9
9
0
50
0
0
0
0
59
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
34
0
0
9
9
42
9
0
0
0
0
0
50
59
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
59
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _